Young Immune Cells, Aging Brains, And Why Cell Storage Matters
A new study in Advanced Science shows that “young” immune cells made from human stem cells can reverse signs of brain aging and Alzheimer’s in mice. Treated animals had better memory, healthier brain cells, and calmer brain inflammation compared with untreated mice.
These cells are called mononuclear phagocytes. In a healthy body they circulate in the blood, clear debris, and help control inflammation, but they become less effective as we age. In this work, researchers created fresh versions of these cells from induced pluripotent stem cells, infused them into aging and Alzheimer’s model mice, and saw memory and neural health improve even though the cells did not enter the brain itself. The effect seems to come from changing signals in the blood that the brain is exposed to.
So, what does this have to do with Immunaeon and cell storage?
Modern therapies are moving toward treatments built from a person’s own cells, including immune cells. CAR T therapies in cancer are already an example, and this new work points to similar possibilities for aging and neurodegenerative disease in the future. All of these approaches depend on having access to enough high quality, healthy cells at the start.
Immunaeon focuses on collecting and cryogenically storing immune cells while they are still strong, long before serious illness or advanced age. We cannot promise to prevent Alzheimer’s or guarantee access to any specific treatment. What we can offer is a way to preserve your immune cells today, so that as therapies like these develop, you already have a bank of your own cells available to be evaluated for future use.
V. A. Moser,